ENZYMATIC ACTIVITIES OF LIVER ASSOCIATED WITH LOW, MODERATE AND HIGH INTENSITIES EXERCISE; A SYSTEMATIC REVIEW

Abstract

This study primarily aimed to assess the modulation of enzymatic activities associated with the low, moderate and high-intensity exercise. A systematic review following the preferred reporting items for systematic reviews and meta-analyses (PRISMA) declaration, and thus the key search engines, i.e. Web of Science, Science Direct, PubMed, Google Scholar and Scopus, were used for the collection of relevant literature. Likewise, studies carried out from 1st July 2018 to 1st July 2024 were included and assessed through the process of qualitative data analysis (QDA) technique. Fifty (50) research studies were retrieved from the key search engines, and finally twenty (2120) studies were evaluated by the application of the Physiotherapy Evidence Scale (PEDro). Based on the ethnicity of the results by following the criteria of PEDro, and thus the results show that low, moderate and high-intensity exercise have a significant impact on the basic liver enzymes, i.e. ALT, ALP and AST. The evidence also indicated that low and moderate-intensity exercise has a more significant impact on the enzymatic activities of the liver; hence, the various supplementations with high-intensity exercise lead to a healthier liver. Hence, no such type of study has been found, which indicates the comparison of various exercise intensities and frequencies with relation to the enzymatic activities of the liver. Based on the key findings of the study, a research study with a solid background needs to be conducted to examine the impact of various exercise intensities and frequencies with the context to enzymatic activities of the liver, with special context to athletes and non-athletes.