HEMATOLOGICAL AND BIOCHEMICAL FEATURE ASSOCIATED TO CHILDERN WITH INTESTINAL HELMINTHS IN DISTRICT KOHAT

Abstract

Intestinal helminth infections remain a significant public health issue, particularly in developing regions. This study investigates the hematological and biochemical profiles of children diagnosed with intestinal helminthiasis in District Kohat, Pakistan. Blood samples were taken from 150 intestinal helminths-infected children, as well as 50 from the control group were taken from children of children up to 12 years. Frequency counts, percentages, averages, standard deviations, and correlations analyzed the data. The stool test revealed that the cyst no and Enterobius vermicularish were found more prevalent in the stool samples of the children. Results of complete blood count (CBC) of 150 confirmed intestinal helminths infection were randomly choosing and compared with CBC reports of non-infected individuals. Albumin to globulin ratio (1.27±0.7), Red Blood Cell (RBC) (4.49±0.56×10⁶/µL), Hemoglobin (HB) (11.64±1.23 g/dL), Mean Corpuscular Volume (MCV) (75.4±3.34 fL) and Neutrophils (57.56±8.43×10³/ µL) were less than mean values of normal. Median values for Total Leukocyte Count (TLC) of both patients and control was almost same and Hematocrit (HCT) (42.16±2.44%), Mean Corpuscular Hemoglobin (MCH) (75.4±3.34 pg), Mean Corpuscular Hemoglobin Concentration (MCHC) (35.03±3.61 g/dL), Platelets (PLT) (291.07±48.7×10³/ µL), Lymphocytes (31.53±9.22×10³/ µL), Monocytes (7.31±3.87×10³/ µL) and Eosinophils (5.09±1.23×10³/ µL) was higher than normal mean values The study aimed to assay some immunological markers and nutritional deficiency in children infected with single or multiple helminths resident in Districts Kohat.